Drink a cup or two of
Scientific and other details of Misai Kuching are documented in major Pharmacopoeia and other Monographs, including
- The European Scientific Cooperative on Phytotherapy 1997 ESCOP
- British Pharmacopoeia 2002
- British Herbal Pharmacopoeia 1997 . BHP
- Complete German Commission E. Commission E
- Martindale 33rd edition
- European Pharmacopoeia 2004 Ph Eur
Unlike modern pharmaceuticals, medicinal or functional plants contain numerous complex active phytochemicals (plant chemicals). Take a look at the list present in Misai Kuching.
|Flavonoid compounds||a) Sinensetin b) Tetramethylscutellarein c) Eupatorin d) Salvigenin e) Cirsimaritin f) Pilloin g) Rhamnazin h) Trimethylapigenin i) Tetramethylluteolin.|
|Diterpene Compounds||a) Orthosiphonone b) Orthosiphonone B c) Orthosiphol A d) Orthosiphol B e) Orthosiphol F f) Orthosiphol G g) Orthosiphol H h) Neoorthosiphols A i) Orthosiphol B j) Staminol A.|
|Benzochromenes|| a) Orthochromene A b) Methylripariochromene A |
|Essential oils||a) β-elemene b) β-caryophyllene c) α-humulene |
d) β-caryophyllene oxide e) Can-2-one f) Palmitic acid
|Others||a) Inosital b) Caffeic acid c) Rosmaric acid  d) β-sitosterol etc.|
Phytochemicals in bold letters have been identified to have beneficial effects. The British Pharmacopoeia and the European Pharmacopoeia have detailed analytical procedures for the testing of Java Tea(Misai Kuching) where Sinensetin is assumed as the marker i.e. the most important phytochemical.
Studies on the Applications of Misai Kuching
The diuretic effects and improved circulation contribute considerably to improving and maintaining health. Some western herbal detox and slimming products add Java Tea to their formulations because of this property.
This is the most extensively studied function of Misai Kuching. A number of animal studies showed diuretic effects with the extracts of Misai Kuching.1.2.3. The phytochemicals Sinensetin and the Tetramethoxy-
flavones "relaxes" the muscles of walls of the internal vessels thus facilitating easier flow of urine and even the small particles that become stones. Methylripariochromene A was found to effect increased urinary flow and the excretion of sodium ions.5. The diuretic effects also explains the traditional use of Misai Kuching not only for urinary tract problems but also for gout, kidney stones7. and high blood pressure.
Modern diuretic medications are often prescribed to treat high blood pressure. The explanation is simple. Reduced water and sodium ions in the blood, lowers the pressure and makes it easier for the heart to pump. In animal studies, the phytochemical Methylripariochromene A was shown to suppress contractions in the thoracic aorta and decrease the contractile force, without significantly affecting the heart beat rate.8. Ten of the other phytochemicals in Misai Kuching tea also exhibited this property to a lesser degree.9.
Experiments using the whole extract of Misai Kuching on laboratory rats produced a significant decrease in blood glucose concentration compared with that in a control group. Comparative experiments with glibenclamide (the standard anti-diabetic drug) showed that similar results could be obtained but only with very high dosage of Misai Kuching.10.
Laboratory studies have shown that Misai Kuching inhibits 15–lipoxygenase, an enzyme thought to be involved in the development of artery blockage by LDL Cholesterol. The inhibitory activity of the whole extract was greater than could be expected from the combined effect of each of the individual flavonoids, which shows that the synergy of the natural whole product is more effective than isolated phytochemicals or synthesised substitutes.11. More recently, studies have shown that Trimethylapigenin, Eupatorin and Tetramethylluteolin were the most effective phytochemicals in Misai Kuching producing this effect..12.
Sinensetin and Tetramethylscutellarein have shown activity against some class of tumour cells, where sinensetin was shown to be more effective than tetramethylscutellarein.13. Orthosiphols A and B have been reported to inhibit tumour promoter 12-O-tetradecanoylphorbol–13–acetate (TPA) in experiments with laboratory mice.14.
Extracts of Misai Kuching leaves have been reported to have activity against skin cancer cell lines in laboratory studies. 15.
Recently Sinensetin has received significant attention in cancer research as it is shown to be an effective chemosensitizer. Chemosensitizers are materials that enhance the therapeutic effects of chemotherapy drugs, particularly with MDR (multi drug resistant) cells.16.
Free radicals (by-products) are produced when the body cells use oxygen. These free radicals cause damage and can lead to problems such as heart diseases, cancer, etc. Substances called antioxidants present in various foods act as "free radical scavengers" mopping up these free radicals. Some of the most potent antioxidants are flavanoid compounds. The numerous flavanoid compounds along with some of the other compounds present in Misai Kuching has qualified it to be one of the most effective antioxidant foodstuff.17. 18.
Contraindications(Adverse interaction with other drugs or herbs)
None known, none reportedSide-effects
None known, none reported
Drink Kuching Herbal tea in the morning and after dinner. You are also advised to practise the healthy habit of drinking adequate fluids.
Premium Misai Kuching Tea
Organic Certification issued by Department of Agticulture, Malaysia
It must be emphasized that all of the above findings show that the effects are mild (with normal dosage) as compared to the effects of modern drugs and cannot be relied on as treatment. However unlike modern drugs, Misai Kuching has no known or reported side effects. Although the extracts of Misai Kuching are used in medicinal formulations by some European companies, Kuching Herbal Tea is promoted, only as functional food. It is especially recommended for people with a family history of the mentioned ailments.
So there you have it – the simple, safe, natural path to good health. Drink a cup or two of Kuching Herbal Tea daily. You will surely appreciate and enjoy it. However, we would like to advise you that not all Misai Kuching tea that is being marketed are the same. You will understand why in next page.
Note: Botanical names for Misai Kuching are Orthosiphon Stamineus, Orthosiphon Aristatus and Orthosiphon Spicatus. Other common names are Kumis Kucing and Java Tea.
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